Dr. Keith Baar, UC Davis — Easy Workouts That Can Restore Tendons (Tennis Elbow, and many others.), Collagen Truth vs. Fiction, Isometrics vs. Eccentrics, JAK Inhibitors, Progress Hormone vs. IGF-1, The Anti-RICE Protocol, and How one can Use Load as an Anti-Inflammatory (#797)

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Dr. Keith Baar, UC Davis — Easy Workouts That Can Restore Tendons (Tennis Elbow, and many others.), Collagen Truth vs. Fiction, Isometrics vs. Eccentrics, JAK Inhibitors, Progress Hormone vs. IGF-1, The Anti-RICE Protocol, and How one can Use Load as an Anti-Inflammatory (#797)

Dr. Keith Baar is a Professor on the College of California, Davis within the Division of Physiology and Membrane Biology.

Throughout his Ph.D. research, his analysis revealed that mechanical pressure on muscle fibers prompts the mammalian goal of rapamycin (mTOR) signaling pathway, a vital regulator of muscular hypertrophy.

Subsequently, he studied the molecular dynamics of skeletal muscle adaptation to endurance coaching beneath the steering of Dr. John Holloszy, a legend within the discipline of train physiology, thought-about the daddy of contemporary train biochemistry.

Constructing on all of this expertise, he carried out analysis into tendon well being and the potential for engineering ligaments, which may have implications for therapy and restoration from accidents.

Dr. Baar now runs the Purposeful Molecular Biology Lab at UC Davis. His lab’s work ranges from finding out molecular adjustments in our cells to conducting research to impact real-world enhancements in individuals’s well being, longevity, and high quality of life.

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Dr. Keith Baar, UC Davis — Easy Workouts That Can Restore Tendons (Tennis Elbow, and many others.), Collagen Truth vs. Fiction, Isometrics vs. Eccentrics, JAK Inhibitors, Progress Hormone vs. IGF-1, The Anti-RICE Protocol, and How one can Use Load as an Anti-Inflammatory

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What was your favourite quote or lesson from this episode? Please let me know within the feedback.

Table of Contents

SELECTED LINKS FROM THE EPISODE

Join with Dr. Keith Baar:

Web site | Bluesky | LinkedIn

Energy Physiology

Molecular Biology

Train Physiology

Dietary supplements

Prescribed drugs

Orthobiologics (Critiqued)

Diets

Motion pictures

Analysis

Related Sources

SHOW NOTES

[00:07:12] How I found Keith’s work by way of a tweet about tennis elbow and mountain climbing.
[00:07:54] Emil Abrahamsson’s hangboard coaching protocol.
[00:09:20] The elemental ideas of energy coaching and connective tissue adaptation.
[00:10:36] mTOR complicated 1 and its position in muscle progress.
[00:12:06] Engineered ligaments and the invention of minimal efficient doses for tendon adaptation.
[00:13:50] The refractory interval between optimum tendon loading periods.
[00:16:42] Rapamycin’s results on muscle hypertrophy.
[00:18:49] Protocols for tennis elbow rehabilitation.
[00:20:28] Why isometrics work higher than eccentrics for tendon therapeutic.
[00:22:14] Stress shielding and the way load distribution impacts tendon therapeutic.
[00:29:07] The misperception about eccentric loading for tendon accidents and why velocity issues.
[00:29:58] Very best length for isometric holds (10-30 seconds) primarily based on damage standing.
[00:33:50] My elbow points and present rehab strategy.
[00:36:02] Overcoming vs. yielding isometrics and optimum loading methods.
[00:47:11] Dr. Barr’s motion prescription for my tennis elbow.
[00:52:18] Loading timingpost-surgery and RICE protocol criticism.
[00:56:58] Achilles tendon rehabilitation after surgical procedure.
[01:00:18] Critique of orthopedic suturing strategies and suggestion for resorbable sutures.
[01:04:02] Anumber of place isometrics for tennis elbow rehabilitation.
[01:07:26] Collagen synthesis, supplementation, and vitamin C timing.
[01:12:59] Critique of BPC-157 and different injectable peptides for tendon therapeutic.
[01:18:19] Analysis of orthobiologics’ (PRP, prolotherapy, stem cells) effectiveness.
[01:21:37] JAK-STAT inhibitor medication and their results on tendon progress.
[01:25:35] Medication that improve danger of tendon ruptures (fluoroquinolones, AT-1 receptor medication).
[01:29:33] How estrogen impacts tendon stiffness and damage danger in ladies.
[01:32:48] Testosterone’s reverse results on tendon in comparison with estrogen.
[01:35:31] Protein consumption suggestions and timing.
[01:40:11] Ketogenic weight loss plan results on mitochondrial biogenesis and longevity.
[01:41:57] Comparability of ketogenic weight loss plan, low protein weight loss plan, and rapamycin for longevity.
[01:47:19] Irritation’s position in adaptation and when to cut back it.
[01:51:17] Timing of ice baths relative to coaching for optimum restoration.
[01:52:33] Parting ideas.

MORE DR. KEITH BAAR QUOTES FROM THE INTERVIEW

“The primary value to the US medical system is definitely musculoskeletal sprains, strains and tears, the again and the neck, in addition to the remainder of the physique. It’s greater than diabetes and coronary heart illness mixed.”
— Dr. Keith Baar

“If passive flexibility was actually essential for lowering tendon damage, then the ladies’s gymnasts who’ve essentially the most passive flexibility wouldn’t be the NCAA sport with the best price of Achilles tendon rupture.”
— Dr. Keith Baar

“Damage associated to flexibility is a U-shaped curve. So our accidents are actually excessive after we’re very rigid. Once we get into that candy spot the place we now have good mobility, we are able to do the total vary of movement, really the damage price could be very low. If we grow to be hyper-mobile, we even have that damage price go up as effectively.”
— Dr. Keith Baar

“We don’t use a ketogenic weight loss plan if we need to go quick, but when we’re coaching for all times, we see that it will increase longevity, that the ketones themselves are actually good for mind operate.”
— Dr. Keith Baar

“The primary recorded immobilizer for an ankle or a leg is from Egyptian hieroglyphs the place they confirmed footage 4,500 years in the past. If I took you and also you mentioned you had most cancers, you wouldn’t need a therapy that was developed 4,500 years in the past. You’ll hope that one thing new has been developed within the final 4,500 years. That’s the place we’re for our orthopedic conditions.”
— Dr. Keith Baar

“The truth is that there are particularly sure athletes like climbers the place they’re doing every kind of heavy lifts, they’re doing every kind of heavy work, they’re doing every kind of actually dynamic strikes. And what occurs, what breaks down is that they break down of their finger tendons they usually break down within the little pulleys throughout the tendons.”
— Dr. Keith Baar

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